Assessment of acute and chronic toxicity of water-soluble polyguanidines towards hydrobionts

4th School-Seminar of Young Russian Scientists "Problems of Sustainable Regional Development", dedicated to the 70th anniversary of Academician of the Russian Academy of Sciences Arnold Kirillovich Tulokhonov

自然科学（总论）

Stelmakh, S.A.^1 ; Grigor'Eva, M.N.^1 ; Tikhonenkov, D.V.^2 ; Ochirov, O.S.^1 ; Mognonov, D.M.^1

Baikal Institute of Nature Management SB RAS, Ulan-Ude

670047, Russia^1

Papanin Institute for Biology of Inland Waters RAS, Borok

152742, Russia^2

关键词: Aliphatic amines;    Chronic toxicity;    Guanidine hydrochloride;    Macromolecular chain;    Polymer structure;    Polymeric compounds;    Threshold levels;    Unicellular organisms;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/320/1/012047/pdf
DOI  :  10.1088/1755-1315/320/1/012047

学科分类：自然科学（综合）

来源: IOP

【 摘 要 】

There were obtained water-soluble polyguanidines of various structures and molecular weights by polycondensation in the melt of aliphatic amines and guanidine hydrochloride in the presented report. There was assessed the toxicity of a number of polymeric compounds in the acute and chronic experiment on fish. In turn this allowed the visionof the link between the structure of the macromolecular chain and toxic action. There was established the average fatal concentration and the threshold level of the fatal effect, which does not exceed the range of 0.5-2.5 mg/l for different polymer structures. Taking into account the fact that such concentrations are destructive for many unicellular organisms, it is possible to predict their high efficiency in the fight against ectoparasites of fish.