Determination of fibrin age in pathologically changed tissues in porcine reproductive and respiratory syndrome

International Scientific Conference «AGRITECH-2019: Agribusiness, Environmental Engineering and Biotechnologies»

农业科学;生态环境科学;生物科学

Stafford, V.V.^1 ; Strel'Tsova, Ya.B.^1

Federal State Budget Institution Federal Scientific Center VIEV, 24-1, Ryazanskiy avenue, Moscow

109428, Russia^1

关键词: Histological section;    Internal organs;    Lymph node tissues;    Natural conditions;    Orange-red;    Pathological changes;    Pathological data;    Vascular system;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/315/4/042029/pdf
DOI  :  10.1088/1755-1315/315/4/042029

来源: IOP

【 摘 要 】

The paper presents data supplementing the pathogenesis of porcine viral reproductive and respiratory syndrome. It was shown that the pathological changes taking place are characteristic both for animals infected under natural conditions and for experimental infection of piglets. Pathological data reflecting the development of pathology in the skin and in the internal organs of piglets indicate the development of systemic pathology affecting the hepato-linear, immune, respiratory and vascular system. The use of specific staining for fibrin showed its effect on the development of pathology not only in the respiratory system, but also in immunocompetent tissues. Specific staining for fibrin in histological sections of lung and lymph node tissues made it possible to determine that "young" fibrin coagulates in the tissues for 6 hours and becomes yellow-orange; "Mature" fibrin stays longer in the body for up to 24 hours and is painted depending on the period in orange-red (6-12 hours), bright red (12-18 hours) and red-violet (18-24 hours), then turning into the "old" fibrin, which is painted in purple (more than 24 hours) and grey-blue (more than 48 hours).