Regulatory effect of essential oils on the production of primary and secondary biogenic free radicals in vitro

International Scientific Conference «AGRITECH-2019: Agribusiness, Environmental Engineering and Biotechnologies»

农业科学;生态环境科学;生物科学

Lesovskaya, M.I.^1 ; Shaporova, Z.E.^1

Institute of Economics and Management of the Agro and Industrial Complex, FGBOU VO, Krasnoyarsk State Agrarian University, Ministry of Agriculture of Russia, Mira ave. 90, Krasnoyarsk

660099, Russia^1

关键词: Anti-oxidant activities;    Basal activities;    Chemical forms;    Experimental modeling;    Human bloods;    Modulating effect;    Peppermint essential oil;    Regulatory effects;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/315/2/022001/pdf
DOI  :  10.1088/1755-1315/315/2/022001

来源: IOP

【 摘 要 】

Using molecular enhancers of chemiluminescence, the regulatory effects of several essential oils on the production of primary and secondary biogenic free radicals in vitro were investigated. For the more correct extrapolation of the results, the human blood phagocytes as biogenic source of free radicals was used in an experimental model during latex stimulation and without it. The antioxidant activity of pine essential oil against primary and secondary biogenic radicals was identified, and the prooxidant activity of eucalyptus essential oil against primary and secondary biogenic radicals was determined. Unlike both of these substrates, the modulating effect of lavender essential oil was identified. Under the influence of this substance luminol-dependent chemiluminescence increased, while lucigenin-dependent chemiluminescence decreased without changing the basal activity of phagocytes. Essential oils of lemon and peppermint acted as radical-specific antioxidants. Under the influence of peppermint essential oil, the production of primary not secondary radicals decreased significantly. Under the influence of lemon essential oil, the production of secondary radicals decreased while production of superoxide did not change significantly. Based on the results are obtained, it is possible to develop or adjust the schemes of health-improving and preventive procedures, as well as to optimize the choice of adaptogens chemical forms.