12th Congress of Indonesian Soc. for Biochemistry and Molecular Biology in Conjunction With The 2nd Int. Conf. "Collaboration Seminar of Chemistry and Industry | |
Expression Of Runx2 And Osteoblast Cell On The Periodontal Of Diabetes Mellitus Wistar Rat With Diet Extract Lemuru Fish Oils Treatment | |
生物科学;化学 | |
Damaiyanti, W.D.^1 ; Parisihni, K.^1 ; Mulawarmanti, D.^1 ; Kurniawan, H.^2 ; Widyastuti^2 | |
Oral Biology Department, Faculty of Dentistry, Universitas Hang Tuah, Jl Arif Rahman Hakim 150, Surabaya, Indonesia^1 | |
Periodontic Department, Faculty of Dentistry, Universitas Hang Tuah, Jl Arif Rahman Hakim 150, Surabaya, Indonesia^2 | |
关键词: Bone destruction; Diabetes mellitus; Fish oil; Immunohistochemistry; Innovative strategies; Osteoblast cells; Periodontal tissue; RUNX2; | |
Others : https://iopscience.iop.org/article/10.1088/1755-1315/217/1/012057/pdf DOI : 10.1088/1755-1315/217/1/012057 |
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学科分类:生物科学(综合) | |
来源: IOP | |
【 摘 要 】
The purpose of this study was to find an innovative strategy for controling progresivity of bone destruction on periodontal that caused by diabetic condition. Methods: Wistar rats sample are devided into 4 group; negative control group, 3 group with lemuru fish oil supplementation (4ml/kg of weight t, 8ml/kg of weight and 16ml/kg of weight). One week before treatment all group induced with STZ 65ml/KgBB and nicotinamide 110ml/KgBB to produced diabetes conditions. Immunohistochemistry slide of periodontal tissue was prepare after 3 weeks therapy. RUNX2 was count using HSCORE index, and osteoblast cell amount was count using image raster by optilab program. Results: Statistical analyses demonstrated a significant increase of RUNX2 expression in negative control group compare to treatment group (p
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Expression Of Runx2 And Osteoblast Cell On The Periodontal Of Diabetes Mellitus Wistar Rat With Diet Extract Lemuru Fish Oils Treatment | 202KB | download |