Study on the application of embolization materials of polyvinyl alcohol particles

2019 International Conference on Advanced Materials and Technology for Sustainable Life

Wang, Na^1 ; Gao, Jialin^2 ; Wu, Yu^3 ; Han, Wei^1

Department of Anesthesiology, First Hospital of Jilin University, China^1

Department of Urology, First Hospital of Jilin University, China^2

Department of Otorhinolaryngology, First Hospital of Jilin University, China^3

关键词: Application fields;    Blood compatibility;    Clinical application;    Clinical treatments;    Expansion coefficients;    Experimental research;    Polymer materials;    Surface materials;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/587/1/012006/pdf
DOI  :  10.1088/1757-899X/587/1/012006

来源: IOP

【 摘 要 】

The application, advantages and disadvantages of PVA particle embolization materials were analyzed retrospectively, and the correlation between the application field and the choice of embolization materials was discussed, which provided a reference for clinical treatment. Relevant literatures in PubMed and Web of Science databases were searched, and the literature on clinical application and experimental research of embolic materials was systematically evaluated. The embolization mechanism, advantages and disadvantages, and clinical application of PVA particle embolization materials were discussed. Polyvinyl alcohol particles are such kind of polymer material that insoluble in water, high expansion coefficient, mechanical embolization of blood vessels, no sensitization reaction, no systemic acute toxicity, no intradermal stimulation reaction, safe and effective use. The adhesive liquid embolism material has no vascular toxicity and has been widely used. The application and upgrading of thrombolytic surface materials can significantly improve the blood compatibility of the materials. All kinds of embolic materials have their own advantages and disadvantages, and none of them can be suitable for all diseases. Therefore, it is very important to choose suitable embolic materials for safe and effective treatment.