Gold nanorods and a nanocomposite material based on them: analytical possibilities for spectrophotometric determination of total catecholamines

Fourth interdisciplinary scientific forum with international participation "New materials and promising technologies"

Gorbunova, M.V.^1 ; Shlenova, A.O.^1 ; Klimenko, R.V.^1 ; Gutorova, S.V.^1 ; Apyari, V.V.^1 ; Dmitrienko, S.G.^1

Department of Chemistry, Lomonosov Moscow State University, Leninskie gory, 1/3, Moscow

119991, Russia^1

关键词: Blood serum;    Gold nanorod;    HPLC analysis;    Model mixtures;    Radar chart;    Spectrophotometric determination;    Standard addition method;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/525/1/012012/pdf
DOI  :  10.1088/1757-899X/525/1/012012

来源: IOP

【 摘 要 】

Gold nanorods and nanocomposite material based on them were synthesized and used as spectrophotometric reagents for determination of catecholamines. Approaches to the determination of total catecholamines content are discussed. Use of radar charts for evaluation of the error of catecholamines determination and for selection of the appropriate standard substance is proposed. Developed spectrophotometric techniques were used for determination of total catecholamines in a model mixture, urea samples and diluted blood serum. Accuracy of the techniques was proved by the standard addition method and by results of HPLC analysis.