Synthesis of eugenol-based selective membrane for hemodialysis

13th Joint Conference on Chemistry

Djunaidi, Muhammad Cholid^1 ; Wenten, I Gede^2

Chemistry Department, Faculty of Mathematics and Natural Sciences, Diponegoro University, Indonesia^1

Chemical Engineering Department, Faculty of Industrial Technology, Bandung Institute of Technology, Indonesia^2

关键词: 1-methyl-2-pyrrolidone;    Distilled water;    Eugenol;    Hemodialysis membranes;    Imprinted membranes;    Molecularly imprinted membranes;    Selective membranes;    Vitamin B-12;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/509/1/012069/pdf
DOI  :  10.1088/1757-899X/509/1/012069

来源: IOP

【 摘 要 】

Research on the synthesis of eugenol-based imprinted hemodialysis membranes has been undertaken. This study aims to produce eugenol-based urea selective membrane for hemodialysis. Eugenol containing functional groups of N and S tied with urea mixed with Poly Viniyl Acetate (PVA), Poly Ethylene Glycol Diglicidyl Ether (PEGDE) crosslinker and 1 Methyl 2 Pyrrolidone (NMP) solvent was heated at 110° to form hydrogel. The hydrogel was then reconstituted in the NMP and fed into the petridisc to form the membrane. The membrane was released the urea bonded with distilled water to obtain Molecularly Imprinted Membrane (MIM)-urea. The resulting MIM urea was characterized using FTIR, SEM. MIM urea was used to transport urea, creatinine and vitamin B-12. The research variables were thickness of membrane and comparison of transport result with NIM (Non Imprinted Membrane). The results obtained were MIM urea transported urea better than NIM. The result obtained was the thinner the membrane the better the urea transport. Membrane was also capable of transporting creatinine but not of transporting vitamin B-12.