Pregnancy is a period of great physiological changes to the mother and foetus. Self-medicationhabits during this phase is very delicate and may sometimes endangerer both mother and foetus. Globally,self-medication practice during pregnancy has been increasing and found to be high in many regions of theworld, especially in developing countries. The type, extent, and reasons for its practice however vary.Studies showed that both modern and herbal medicines are commonly used for self-medication indeveloping countries. To identify the prevalence and distribution of self-medication among pregnantwomen in urban area. 200 pregnant mothers based on convenient sampling were involved in the currentstudy. The questionnaire was prepared based on previous literature study and administered through face- to-face interview method. The data collected was coded and entered in Microsoft office excel worksheetand analysed using trial version SPSS. Descriptive statistics was done and the results were 79% werepractising selfmedication. 80% followed Herbal medicine as a mode of self medication. 82%followedselfmedication for indigesition and merely 4.5% for cough and cold, 4% headache, 2.5% morningsickness and 2.5% for vomiting.92.5% of them knew this is a dangerous habit, 77.5% of them gainedknowledge regarding the habit from ffriends, parents, relatives. 78% of them revealed the reason for self- medication as easy availability of medicine.94% were not aware regarding the hazardous effect of self- medication. 94.5% suggested awareness campaign to educate regarding cessation of self-medication habit.Self-medication among pregnant women urban field practicing area found to be high and the reasonsbehind islack of awareness, easy availability of drugs and difficulty in access to health services. There is aneed to impervious awareness among the public regarding the danger’s of self medication habit looming incommunity.

Urinary tract infections (UTIs) are one of the most common infectious diseases encountered inthe clinical practice. Extended spectrum beta lactamases (ESBLs) production in gram negative bacteria,have emerged as a major problem in hospitalized as well as community based patients. Bacterialresistance to β-lactam antibiotics has risen dramatically, with ESBL contributing to this increase. Earlyidentification of ESBL production is becoming increasingly important. The objective of this study was todetermine the resistance patterns of the micro-organisms isolated from cases of UTI and to detect ESBLsproduction in gram negative bacteria. Uropathogens from symptomatic UTI cases were identified byconventional methods, over the period of eight months. Antimicrobial susceptibility testing wasperformed by Kirby Bauer's disc diffusion method. Gram negative isolates resistant to third generationcephalosporins were tested for ESBL production by two methods ( Modified Double disc synergy test(DDST) and Phenotypic confirmatory disc diffusion test (PCDDT)). Number of urinary isolates were 175over a study period of six months. E.coli was the predominant isolate 101 (57.7%). A total of 170 Gramnegative isolates resistant to third generation cephalosporins were tested for ESBL production. It wasobserved that ESBL production was present in13 isolates by DDST method and in 18 isolates by PCDDTisolates. Routine ESBL testing of all uropathogens along with conventional antimicrobial susceptibility isrecommended for all cases as this will help in the proper treatment of the patients and also preventfurther development of bacterial drug resistance.

The demographic transition leads to rapid growth in industrialization, urbanization and increase in populationwhich in turn results in rapid increase in the number of vehicles on inadequate road width. This transition made theroad traffic accidents as the third most common cause of death among non communicable disease. Objectives of thestudy is to assess the status of head injury using glasscow coma scale among road traffic accidents cases coming to atertiary care hospital in B.G. Nagara, Mandya district, Karnataka state and to know the various epidemiological factors(human and environmental factors) related to road traffic accident cases. A Hospital based descriptive cross-sectionalstudy was undertaken at Adichunchanagiri Hospital and Research Centre, a tertiary care hospital, Nagamangala taluk,Mandya district to assess the status of head injury and epidemiological factors responsible for Road Traffic Accidents.About 1204 RTI victims out of 536 Road traffic accidents were interviewed with a semi structured and pretestedquestionnaire during July 2021 to June 2022. Majority of victims were males (82.1%) in the age group of 15 to 30 years(47.6%). Maximum number of victims were educated up to PUC (27.4%) and 15.4% were illiterates. About 8% ofvictims had head injury with majority showed GCS < 3(58.3%). Majorities were drivers (68.6%) involved with a peakduring weekends (57.4%), in the evening hours (23.8%) and during the month of June (19.1%). About 29.7% gaveinadequate visibility and 18.5% gave alcohol consumption as the reason for the RTA. The current study resultsobserved that males in the productive age group of 15 to 30 years were majority victims of RTA and so makingeconomic loss and burden on the family. Awareness should be created to prevent RTA and its mortality and morbidity.

The pharmaceutical quality management system is a concept of management function that designand implement the “Quality policy”. The pharmaceutical manufacturing industries all over the world havejust begun to apply the United States Food and Drug Administration (USFDA) guidelines in the 21stcentury. The study tries to identify the quality metrics based on Quality Indicators for a pharmaceuticalindustry and to investigate the utilization of quality KPIs. Methodology: The work experience from asuccessfully working pharmaceutical organization related to Research and and Development (R&D) ofpharmaceutical products are discussed here. Important areas were identified and analysed based on thedata collected from the deviation reports of selected organization and other resources. The R&D centreuses a software system for Quality management system including, Deviation management, Changemanagement, Laboratory investigation, Incident management and Corrective Action and PreventiveAction (CAPA).

Medicinal plant life had been used for healing and splendor programs in Sri Lanka withdocumented records of over 2,500 years. This inherited information, which has been exceeded down fromera to era, affords a in large part unexplored supply for the capacity improvement of lively components forbeauty formulations. Therefore, the prevailing complete survey changed into carried out to pick out beautycapacity medicinal plant life species in Sri Lanka. Personal interviews had been carried out through a semistructured questionnaire with randomly decided on 30 conventional practitioners and ninety Ayurvedaphysicians in Sri Lanka. Data had been accrued on plant life and particular plant elements used for theremedy of pores and skin care, hair care, and oral care topically. The received statistics had been validatedthe usage of the Ayurveda real books and quantitatively analyzed the usage of relative frequency of citation(RFC), use value (UV), relative significance (RI), and element informant consensus (FIC). Results discoveredapproximately the use of 133 extraordinary plant species belonging to sixty four households in beautyremedies below the kinds of pores and skin care, hair care, and oral care.In conclusion, received facts maywant to in the end be applied for the improvement of the natural beauty enterprise thru the isolation andcharacterization of bioactive compounds from the documented plant life at the same time as maintainingthe conventional information.

A forty-year-old female presented with lower abdominal pain and dysmenorrhea for the past four tosix months. She had menorrhagia in her previous two cycles. No history of dyspareunia was present. She didnot have any vaginal discharge, fever, or weight loss. There was no past myomectomy or Cesarean delivery.Pelvic examination was unremarkable except for mild tenderness. Lab investigations were within normallimits.