Pathology & Oncology Research

, Volume 6, Issue 4, pp 292–294

Placental site trophoblastic tumor

Clinical and pathological report of two cases
  • Gabriella Arató
  • Vilmos Fülöp
  • Péter Degrell
  • Iván Szigetvári
Case Report
Received:
Revised:
Accepted:

DOI: 10.1007/BF03187334

Cite this article as:
Arató, G., Fülöp, V., Degrell, P. et al. Pathol. Oncol. Res. (2000) 6: 292. doi:10.1007/BF03187334

Abstract

Placental site trophoblastic tumor (PSTT) is the rarest disease of the gestational trophoblast. Our two cases will be interesting not only because of the rarity of the disease, but because both were recognized before operation. Since the tumor cells are lined up tightly side by side, this disease must be distinguished primarily from tumors of epithelial origin. The authors highlight that the diagnosis should rely on intense hPL-positivity as well as the ultrastructural image of the tumor. In histologically equivocal cases, the determination of hPL, hCG, and MIB-1 immunologic markers can be recommended as routinely performed morphological examinations. Serum hCG monitoring is recommended to follow the evolution of the tumor.

Keywords

placental trophoblastic tumor choriocarcinoma immunohistology intermediate trophoblast 

Copyright information

© Arányi Lajos Foundation 2000

Authors and Affiliations

  • Gabriella Arató
    • 1
  • Vilmos Fülöp
    • 2
  • Péter Degrell
    • 3
  • Iván Szigetvári
    • 2
  1. 1.Institute of Pathology, Faculty of Health SciencesSemmelweis UniversityBudapestHungary
  2. 2.Department of Obstetrics and GynecologySemmelweis University, Faculty of Health SciencesBudapest
  3. 3.Department of PathologyCounty Hospital of Borsod-Abauj-ZemplenMiskolcHungary

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