Improving diagnostic accuracy of prostate carcinoma by systematic random map-biopsy János Szabó György Hegedûs Katalin Bartók Tibor Kerényi Attila Végh Imre Romics Béla Szende Email author Article Received: 10 February 2000 Accepted: 10 April 2000 DOI :
10.1007/BF03032359
Cite this article as: Szabó, J., Hegedûs, G., Bartók, K. et al. Pathol. Oncol. Res. (2000) 6: 111. doi:10.1007/BF03032359
Abstract Systematic random rectal ultrasound directed mapbiopsy of the prostate was performed in 77 RDE (rectal digital examination) positive and 25 RDE negative cases, if applicable. Hypoechoic areas were found in 30% of RDE positive and in 16% of RDE negative cases. The score for carcinoma in the hypoechoic areas was 6.5% in RDE positive and 0% in RDE negative cases, whereas systematic “map” biopsy detected 62% carcinomas in RDE positive, and 16% carcinomas in RDE negative patients. The probability of positive diagnosis of prostate carcinoma increased in parallel with the number of biopsy samples/case. The importance of systematic map biopsy is emphasized.
Keywords map-biopsy prostate carcinoma RDE
References 1.2
Resnick MI : Transrectal ultrasound guided versus digitally directed prostatic biopsy: A comparative study. J Urol 139:754–757, 1988.
PubMed Google Scholar 2.2
Hodge KK, McNeal JE, Stanley TA : Ultrasound guided transrectal core biopsies of the palpably abnormal prostate. J Urol 142:66–70, 1989.
PubMed Google Scholar 3.2
Lippman HR, Ghiatas AA, Sarosdy ME : Systematic transrectal ultrasound guided prostate biopsy after negativ digitally directed prostate biopsy. J Urol 147:827–829, 1992.
PubMed Google Scholar 4.2
Terris MK, McNeal JE, Stamey TA : Detection of clinically significant prostate cancer by transrectal ultrasound guided systematic biopsies. J Urol148:829–832, 1992.
PubMed Google Scholar 5.2
Irwin MB, Trapasso JG, Stamey TA : Identification of insignificant prostate cancers. Analysis of preoperative parameters. Urology 44:862–868, 1994.
PubMed CrossRef Google Scholar 6.2
Devonec M, Fendler JP, Monsallier M, et al The significance of the prostatic hypoechoic area: results in 226 ultrasonically guided prostatic biopsies. J Urol 143:316–319, 1990.
PubMed Google Scholar 7.2
Hodge KK, McNeal JE, Terris MK, et al : Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol 142:71–75, 1989.
PubMed Google Scholar 8.2
Hammerer P, Huland H, Cooner WH : Systematic sextant biopsies in 651 patients reffered for prostate evaluation. J Urol 151:99–104, 1994.
PubMed Google Scholar 9.2
Vallancien G, Prapotnich D, Veillon B, et al : Systematic prostatic biopsies in 100 men with no suspicion of cancer on digital rectal examination. J Urol 146:1308–1312, 1991.
PubMed Google Scholar 10.2
Gasman D, Abbou CC: Biopsies prostatiques: technique, intéréts et complitatious. Entretiens de Bichat Urologie. Abstract. 1995.
11.2
Jewett HJ : Significance of the palpable prostatique nodule. JAMA 160:838–839, 1956.
Google Scholar 12.2
Lee F, Trop-Pedersen S, Littrup PJ, et al : Hypoechoic lesions of the prostate: clinical relevance of tumor size, digital rectal examination, and prostate specific antigen. Radiology 170:29–32, 1989.
PubMed Google Scholar 13.2
Holm HH, Gammelgaard J : Ultrasound guided precise needle placement in the prostate and seminal vesicles. J Urol 125:385–387, 1981.
PubMed Google Scholar 14.2
Cooner WH, Mosley BR, Rutherford Jr
CL, et al : Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen. J Urol 143:1146–1154, 1990.
PubMed Google Scholar 15.2
Topr-Pedersen S, Lee F, Littrup PJ, et al : Transrectal biopsy of the prostage guided with transrectal US: Longitudinal and multiplanar scanning. Radiology 170:23–27, 1989.
Google Scholar 16.2
Coplen DE, Andriole GL, Yuan JJJ et al : The ablity of systematic transrectal ultrasound guided biopsy to detect prostate cancer in men with the clinical diagnosis of benign prostatic hyperplasia. J Urol 146:75–77, 1991.
PubMed Google Scholar 17.2
Vashi AR, Wojno KJ, Henricks W, et al : Determination of the reflex range and appropriate cutpoints for percent free PSA prostate specific antigen in 413 men referred for prostatic evaluation using the AxSYM system. Urology 49:19–27, 1997.
PubMed CrossRef Google Scholar 18.2
William J, Catalona, et al : Evaluation of percentage of free serum prostatic specific antigen to improve specificity of prostate cancer screening. JAMA 274:1214–1220, 1995.
CrossRef Google Scholar © Arányi Lajos Foundation 2000
Authors and Affiliations János Szabó György Hegedûs Katalin Bartók Tibor Kerényi Attila Végh Imre Romics Béla Szende Email author 1. Department of Urology Central Military Hospital Hungary 2. Department of Pathology Central Military Hospital Hungary 3. 2nd Institute of Pathology Semmelweis University Budapest Hungary 4. Department of Urology Semmelweis University Budapest Hungary 5. 1st Institute of Pathology and Experimental Cancer Research Semmelweis University Budapest