Malignant mixed mullerian tumor of the extra-genital coelomic epithelium: Report of two cases Irene G Ibanez-Manlapaz David McCoy Vincent Vincent Ulla Jo Ule Case Report Received: 10 February 1997 Accepted: 05 April 1997 DOI :
10.1007/BF02907808
Cite this article as: Ibanez-Manlapaz, I.G., McCoy, D., Vincent, V. et al. Pathol. Oncol. Res. (1997) 3: 130. doi:10.1007/BF02907808 Abstract Malignant mixed mullerian tumors of the extra-genital coelomic epithelium (female peritoneum) are rare. Since the first case report in 1955, only nineteen have been described. In our Case 1 a 58 year-old G3P3 (gravidity = 3; parity = 3) white female with mixed mullerian tumor, homologous type, involving the abdominal peritoneum was treated with surgery and chemotherapy (doxorubicin hydrochloride and cis-platinum). She died of the disease 20 months after initial surgery. Case 2 is a 75 year-old G0P0 (gravidity = 0; parity = 0) white female with mixed mullerian tumor containing heterologous elements involving the pelvic peritoneum who was treated with surgery and chemotherapy (ifosfamide with mesna). She relapsed 6 months after surgery and refused any further treatment. She died 2 weeks later. These cases support the fact that malignant mixed mullerian tumor of the female peritoneum is rare and usually affects elderly females. It has poor prognosis and among the 15 reported cases with follow-up indicating time and presence of disease at death, only 5 survived more than 12 months after initial surgery.
Key words extra-genital mullerian tumor carcinosarcoma poor prognosis female peritoneum
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Authors and Affiliations Irene G Ibanez-Manlapaz David McCoy Vincent Vincent Ulla Jo Ule 1. Departments of Pathology St. Frances Cabrini Hospital Alexandria USA 2. Surgery St. Frances Cabrini Hospital Alexandria USA 3. Obstetrics & Gynecology St. Frances Cabrini Hospital Alexandria USA 4. Medicine St. Frances Cabrini Hospital Alexandria USA