Eosinophils and mast cells inHelicobacter Pylori infected gastric mucosa Lajos Berczi Email author Klára TamÁssy Béla Fekete László Kopper Article Received: 05 October 1996 Accepted: 22 November 1996 DOI :
10.1007/BF02904816
Cite this article as: Berczi, L., TamÁssy, K., Fekete, B. et al. Pathol. Oncol. Res. (1996) 2: 237. doi:10.1007/BF02904816 Abstract Although Helicobacter pylori (HP) is frequently associated with chronic active gastritis and peptic ulcers, its exact pathogenic role or the pathomechanism is still unclear. Here, we describe a striking, statistically significant increase of eosinophils in HP infected gastric mucosa compared to HP negative gastritis with similar activity. In both cases, the mean number of the mast cells in the mucosa was comparable, although the individual values showed wide distribution. The source and role of eosinophilia in HP infected mucosa, the potential link between the degree of eosinophilia and the clinical progression, as well as between eosinophils and mast cells require further study.
Key words eosinophilia gastritis Helicobacter pylori This work was supported by a scientific research grant No T-05702/903 from the Ministry of Welfare
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Authors and Affiliations Lajos Berczi Email author Klára TamÁssy Béla Fekete László Kopper 1. 1st Institute of Pathology and Experimental Cancer Research Semmel weis University of Medicine Budapest 2. Teaching Hospital Semmel weis University of Medicine Budapest 3. Institute of Pathology Semmelweis Medical University Budapest Hungary