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1 γH2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments [期刊论文]

来源：BMC Cancer

作者:Andrew J Massey, Rebecca Rawlinson

关键词:Combination therapy;Biomarker;...

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2 SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation [期刊论文]

来源：BMC Cancer

作者:Yue Dai;Yu-Feng Xia;Ling-Yi Kong;等

关键词:Cell cycle arrest;DNA damage;...

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3 SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation [期刊论文]

来源：BMC Cancer

作者:Yue Dai;Yu-Feng Xia;Ling-Yi Kong;等

关键词:Cell cycle arrest;DNA damage;...

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4 Genetic inhibition of the atypical kinase Wee1 selectively drives apoptosis of p53 inactive tumor cells [期刊论文]

来源：BMC Cancer

作者:Jieyi Wang;Chris Tse;Lora A Tucker;等

关键词:DNA damage;CDK2;...

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5 An aza-macrocycle containing maltolic side-arms (maltonis) as potential drug against human pediatric sarcomas [期刊论文]

来源：BMC Cancer

作者:Katia Scotlandi;Mirco Fanelli;Vieri Fusi;等

关键词:Macrocycles;Apoptosis;...

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6 Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening [期刊论文]

来源：BMC Cancer

作者:Jun Liu;Jennifer L Harris;Serge Batalov;等

关键词:DNA repair;DNA damage;...

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