The role of surgical resection in managements of brain metastasis: A 17-year longitudinal study

brain;metastasis;surgery;survival;outcome

의과대학 의학과 ;

University:서울대학교 대학원

关键词: brain;    metastasis;    surgery;    survival;    outcome;   

Others  :  http://s-space.snu.ac.kr/bitstream/10371/132513/1/000000004458.pdf

美国|英语

来源: Seoul National University Open Repository

【 摘 要 】

STR, P=.075). There were no significant survival differences by clinical characteristics (age, gender, number of lesion, and histology of systemic disease). Overall local recurrence occurred in 15.7% of these patients. The local recurrence rate was 14.6% in GTR and 18.2% in STR (P=.589). Overall distant metastasis was detected in 43 patients (29.5%). The KPS score in the GTR group was changed from 82.3 to 87.0, and that in the STR group changed from 79.2 to 77.1 (P=.001). Postoperative complications occurred in 7 patients (4.5%). Two STR cases (1.3%) expired due to uncontrolled brain swelling and intracerebral hemorrhage.ConclusionSurgical resection shows favorable outcome in aspect of survival and clinical outcome. The extent of surgical resection, RPA class, and the status of extracranial condition are important prognostic factors in overall survival. Even in advancement of adjuvant therapies, surgical resection plays a major role in management of brain metastasis.