The effect of hypothermia on the NLRP3 inflammasome expression in a rat model of focal cerebral ischemia

hypothermia;cerebral ischemia;inflammasome;610

의과대학 의학과 ;

University:서울대학교 대학원

关键词: hypothermia;    cerebral ischemia;    inflammasome;    610;   

Others  :  http://s-space.snu.ac.kr/bitstream/10371/132727/1/000000025094.pdf

美国|英语

来源: Seoul National University Open Repository

【 摘 要 】

p<0.001 with NLRP3 antibody).Conclusion: Our study revealed that NLRP3 inflammasome is overexpressed in the BV-2 microglial cells with OGD models, and hypothermia attenuates the NLRP3 inflammasome expression and infarct volume in a rat model of focal cerebral ischemia.