Objective: This study aims to evaluate the effect of dentifrice formulations containing Centella asiatica (CA) and bamboo salt (BS) on gingivitis and dental plaque.Methods: A 4-day randomized crossover clinical trial with 10-day washout period was applied for two experimental dentifrices and a standard-control dentifrice (Control). Thirty-three volunteers with the mean age of 28 yearswere randomized into 3 groups. One experimental dentifrices contained Control plus CA (DCA) and the second experimental dentifrice contained and additional component of BS (DCA-BS). Each participant used the assigned dentifrices to brush their teeth for 3 minutes twice a day. Pre- and post-experiment clinical examinations of the upper teeth were performed. The gingival index (GI) was assessed using CPI probe at 60 gingival sulcus sitesamong 10 teeth. Turesky-modified plaque index (PI) was assessed in 30 tooth surfaces of 10 teeth. The difference between pre- and post-experimental data was analyzed using Wilcoxon signed-rank test for GI and paired t-test for PI. Wilcoxon signed-rank test was also used to compare treatment efficacy.Results: DCA-BS reduced GI by 72% after experiment. Compared to Control, the GI reduction ratio of DCA-BS was 3.3 times. However, there was no difference in the effect on PI among DCA-BS, DCA and Control. Our data showed that the new dentifrices containing CA and BS could reduce the risk of gingivitis. Further study is indicated.Conclusions: The dentifrices containing CA and BS could be used to promote gingival health in young adults in both home care and clinical application.
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The effect of new dentifrices containing Centella asiatica and Bamboo salt on reducing plaque and gingivitis - a randomized clinical trial -
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