older age (p=.009), lower income (p=.003), the higher number of diseases (p<.001), the higher number of medications (p<.001), and lower perceived health status (p<.001). On the other hand, gender, education, and body mass index (BMI) were found to be unrelated to fatigue. In multiple linear regressions, (the explanatory power, 47.5%), fatigue increases with older age (p<.001), depression (p<.001), pain (p=.001), irregular exercise (p=.013), and lower perceived health status (p<.001). In conclusion, our study results suggest that depression, pain, and regular physical activity were identified as manageable risk factors for fatigue alleviation of elderly people. Therefore, these factors should be considered when developing fatigue management programs for elderly people.