MEMS-based nozzles and templates for the fabrication of engineered tissue constructs

Microvascular scaffolds;Tissue scaffold;Collagen microfibers;MEMS;Micro/nanonozzles

Naik, Nisarga ; Electrical and Computer Engineering

University:Georgia Institute of Technology

Department:Electrical and Computer Engineering

关键词: Microvascular scaffolds;    Tissue scaffold;    Collagen microfibers;    MEMS;    Micro/nanonozzles;   

Others  :  https://smartech.gatech.edu/bitstream/1853/42853/1/naik_nisarga_n_201012_phd.pdf

美国|英语

来源: SMARTech Repository

【 摘 要 】

This dissertation presents the application of MEMS-based approaches for the construction of engineered tissue substitutes. MEMS technology can offer the physical scale, resolution, and organization necessary for mimicking native tissue architecture. Micromachined nozzles and templates were explored for the fabrication of acellular, biomimetic collagenous fibrous scaffolds, microvascular tissue structures, and the combination of these structures with cell-based therapeutics. The influence of the microstructure of the tissue constructs on their macro-scale characteristics was investigated.