Knotless Bi-directional Barbed Absorbable Surgical Suture

suture;Biomaterial;textile;knotless

Dattilo, Philip P Jr. ; Dr. Martin W. King, Committee Chair,Dr. Abdelfattah Seyam, Committee Member,Dr. David R. Buchanan, Committee Member,Dattilo, Philip P Jr. ; Dr. Martin W. King ; Committee Chair ; Dr. Abdelfattah Seyam ; Committee Member ; Dr. David R. Buchanan ; Committee Member

University:North Carolina State University

关键词: suture;    Biomaterial;    textile;    knotless;   

Others  :  https://repository.lib.ncsu.edu/bitstream/handle/1840.16/65/etd.pdf?sequence=1&isAllowed=y

美国|英语

来源: null

【 摘 要 】

With the objective of eliminating the adverse effects of traditional sutures, a novel knotless bi-directional barbed monofilament absorbable suture has been developed that does not require surgical knots for security. First the study focused on developing a method for characterizing the individual barbs as well as the bi-directional barbs for the whole suture.The method proved effective in characterizing the individual barb's geometry in terms of cut angle, cut depth, and a calculated cut length, as well as characterizing the left and right sections of the knotless suture in terms of the distance between cuts and the number of cuts per unit length. Second the study focused on developing an in vitro method to measure wound holding capacity.Wound holding capacity was measured in two ways, first by evaluating the load required to give a 2 mm of separation of tissue at the wound, and secondly by and evaluating the area of tissue separation at a given load.The wound holding capacity of a knotless barbed suture at 2 mm of separation was found to be 27.72 ± 8.32 N compared to a traditional monofilament knotted control suture of 15.25 ± 3.36 N.At a given load of 11.12 N the area of separation was zero compared to the traditional monofilament control suture that yielded an area of separation of 3.38 ± 2.37 mm2.The study was effective in developing test methods for characterizing the knotless suture geometry as well as developing an experimental method for measuring wound holding capacity.No significant difference in wound holding performance was found among barbed suture samples cut at different barb angles.