Moderation by depression and anxiety of connectivity among brain areas associated with motivation

Approach motivation;avoidance motivation;depression;anxiety

Spielberg, Jeffrey M.

关键词: Approach motivation;    avoidance motivation;    depression;    anxiety;   

Others  :  https://www.ideals.illinois.edu/bitstream/handle/2142/26407/Spielberg_Jeffrey.pdf?sequence=1&isAllowed=y

美国|英语

来源: The Illinois Digital Environment for Access to Learning and Scholarship

【 摘 要 】

Pathological anxiety and depression are prevalent forms of psychopathology and are associated with significant impairment in multiple areas of life, including occupational and social functioning. Although both forms of psychopathology have been heavily researched, the factors involved in their etiology and maintenance are still a matter of debate and require further investigation. Levels of trait approach and avoidance motivation may be relevant for understanding the differential correlates of anxiety and depression, given research indicating that they have distinct relationships with dimensions of trait motivation. An integrative model of the brain regions instantiating the approach and avoidance motivational systems is needed to understand how dysfunction in these systems manifests in anxiety and depression.The present dissertation aims to advance these literatures by proposing a hierarchical model of the neural components implementing the approach and avoidance motivational systems and examining the functional relationships among the proposed brain regions for motivational control. This model is then used to delineate areas of motivational dysfunction associated with pathological anxiety and depression.