A fast optical imaging study of frontoparietal preparatory dynamics in response-mode switching

frontoparietal network;task switching;response preparation;executive control;functional connectivity;optical imaging;event-related brain potentials

Baniqued, Pauline ; Fabiani ; Monica ; Gratton ; Gabriele

关键词: frontoparietal network;    task switching;    response preparation;    executive control;    functional connectivity;    optical imaging;    event-related brain potentials;   

Others  :  https://www.ideals.illinois.edu/bitstream/handle/2142/42453/Pauline_Baniqued.pdf?sequence=1&isAllowed=y

美国|英语

来源: The Illinois Digital Environment for Access to Learning and Scholarship

【 摘 要 】

Coordination between networks of brain regions is important for optimal cognitive performance, especially in attention demanding tasks. With the event-related optical signal (EROS; a measure of changes in optical scattering due to neuronal activity) we can characterize rapidly evolving network processes by examining the millisecond-scale temporal correlation of activity in distinct regions during the preparatory period of a response-mode switching task. Participants received a pre-cue indicating whether to respond vocally or manually. They then saw or heard the letter “L” or “R”, indicating a “left” or “right” response to be implemented with the appropriate response modality. We employed lagged cross-correlations to characterize the dynamic connectivity of preparatory processes. Our results confirmed coupling of frontal and parietal cortices, and the trial-dependent relationship of the right frontal cortex with response preparation areas. The frontal-to-modality-specific cortex cross-correlations revealed a pattern in which first irrelevant regions were deactivated and then relevant regions were activated.These results provide a window into the sub-second-scale network interactions that flexibly tune to task demands.