Psychiatric aspects of migraine. Literature review. This section provides a survey of the literature on the multiple factors implicated in the aetiology of migraine and the links between migraine and psychiatric disorder. The relationship between epilepsy and migraine is reviewed. Olfactory auras in epilepsy are associated with depression. Cocaine abuse is suggested as a model for migraine hallucinations and the precipitation of psychiatric illness by stress. Endorphins are released along with stress hormones and are likely to play an, as yet, unspecified role in the production of stress-related psychiatric and physical illness. They are clearly involved in the experience of pain in migraine and possibly also in mood changes. Menstrual migraine is accepted as a subgroup of migraine although it can be defined objectively much less frequently than it is subjectively complained of. Finally cerebral asymmetry in physiology and cognition is discussed as it applies to migraine.
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