Genomic Variation in the Canine Adenoviruses

Veterinary science, Animal diseases, Virology

Cavanagh, Heather Margaret Ann

University:University of Glasgow

关键词: Veterinary science, Animal diseases, Virology;   

Others  :  http://theses.gla.ac.uk/76899/1/10970947.pdf

来源: University of Glasgow

【 摘 要 】

Considerable differences exist in the pathogenicity of wild-type and vaccine strains of canine adenovirus. An analysis of their genome structure was undertaken in orrder to investigate the molecular basis of their differing pathogenicities. Six vaccine strains and two wild-type strains were examined. Preliminary investigations revealed significant variation near the genome termini.