Energy Expenditure and Substrate Metabolism in Patients With Cancer and Weight Loss

Medicine, Oncology

Hansell, Douglas Thomson

University:University of Glasgow

关键词: Medicine, Oncology;   

Others  :  http://theses.gla.ac.uk/77391/1/10991853.pdf

来源: University of Glasgow

【 摘 要 】

Cachexia is commonly seen in patients with cancer, and there is evidence to suggest that these debilitated cancer patients are at an increased risk of morbidity and mortality following surgical procedures. This thesis is concerned with two main avenues of investigation. In the first part, various mechanisms implicated in the development of cancer cachexia have been investigated in weight stable and weight losing patients with cancer and nonmalignant illness. The second part is concerned with ways of influencing the metabolic response in cancer patients undergoing moderate and major surgical procedures.