Titanium-based methylenations and their application to the synthesis of pipecolic acid derivatives

QD Chemistry

Haahr, Adam ; Hartley, R.C.

University:University of Glasgow

Department:School of Chemistry

关键词: Organic chemistry, titanium methylenation, titanium carbenoid, pipecolic acid, piperidinone;   

Others  :  http://theses.gla.ac.uk/3263/1/2011HaahrPhD.pdf

来源: University of Glasgow

【 摘 要 】

This thesis describes the use of titanium carbenoids for the synthesis of piperidinonealkaloids, in particular pipecolic acid derivatives, and the development of a newtitanium-based strategy for the methylenation of carbonyl compounds includingcarboxylic acid derviatives.