Genomic interactions of the transcription factor VEZF1

QH301 Biology;RC0254 Neoplasms. Tumors. Oncology (including Cancer)

Low, Carolyn M. ; West, Adam G.

University:University of Glasgow

Department:Institute of Cancer Sciences

关键词: QH301 Biology;    RC0254 Neoplasms. Tumors. Oncology (including Cancer);   

Others  :  http://theses.gla.ac.uk/5078/1/2013LowPhD.pdf

来源: University of Glasgow

【 摘 要 】

VEZF1 is a highly conserved vertebrate transcription factor. VEZF1 binding sites have been reported to function in gene promoter activation, insulator barrier activity and protection from de novo DNA methylation. This study aims to identify VEZF1 binding sites across the human genome and to develop a better understanding of the gene regulatory processes mediated by VEZF1.