Bringing polyoxometalates to peptide chemistry: a modular approach

QD Chemistry

Yvon, Carine ; Cronin, Leroy

University:University of Glasgow

Department:School of Chemistry

关键词: polyoxometalates;    peptide;    organic-inorganic hybrids;    solid phase peptide synthesis (SPPS);   

Others  :  http://theses.gla.ac.uk/5248/1/2014YvonPhD.pdf

来源: University of Glasgow

【 摘 要 】

This thesis focuses on the development of modular approaches that permit the integration of hybrid polyoxometalates (POMs) into peptide chains. This goal is of considerable interest in the field of POM chemistry, as it could provide a new approach to explore, develop and tune the properties of POM clusters (e.g. toxicity, self-assembly and recognition properties). The organic-inorganic Mn-Anderson cluster, a bi-substituted cluster incorporating two TRIS-based moieties, was used as a model compound to develop these methodologies.