Quantum state discrimination is a fundamental task in the field of quantum communication and quantum information theory. Unless the states to be discriminated are mutually orthogonal, there will be some error in any attempt to determine which state was sent. Several strategies to optimally discriminate between quantum states exist, each maximising some figure of merit. In this thesis we mainly investigate the minimum-error strategy, in which the probability of correctly guessing the signal state is maximised. We introduce a method for constructing the optimal Positive-Operator Valued Measure (POVM) for this figure of merit, which is applicable for arbitrary states and arbitrary prior probabilities. We then use this method to solve minimum-error state discrimination for the so-called trine states with arbitrary prior probabilities - the first such general solution for a set of quantum states since the two-state case was solved when the problem of state discrimination was first introduced. We also investigate the difference between local and global measurements for a bipartite ensemble of states, and find that in certain circumstances the local measurement is superior. We conclude by finding a bipartite analogue to the Helstrom conditions, which indicate when a POVM satisfies the minimum-error criteria.