Effects of raspberry ketone and green coffee bean extract on body mass and substrate utilisation

QP Physiology

Johnston, Lynsey ; MacFarlane, Niall

University:University of Glasgow

Department:School of Life Sciences

关键词: Raspberry ketone, green coffee bean extract, body mass, substrate utilisation.;   

Others  :  http://theses.gla.ac.uk/75166/1/2019JohnstonLMScR.pdf

来源: University of Glasgow

【 摘 要 】

Dietary food supplements are becoming increasingly popular and while many claim to aid weight loss, there is limited evidence to support such claims. Raspberry ketone and green coffee bean extract have both been marketed for weight loss and are often sold in a combined form. The aim of the present study was to test whether raspberry ketone and green coffee bean extract, when consumed separately and in combination, affect substrate utilisation and body composition. In a single blind randomised control trial, 32 healthy recreationally active males and females (age: 30.4 ± 1.5 years; BMI: 26.7 ± 0.4 kg.m-2; body mass: 79.0 ± 1.8 kg; V̇O2max: 37.7 ± 1.4 ml.kg-1.min-1) were randomly assigned to four different treatment groups for 8 weeks; raspberry ketone (RK) (200 mg/day), green coffee bean extract (CGE) (400 mg/day), raspberry ketone plus green coffee bean extract (RK+CGE) (200 mg/day plus 400 mg/day) or control (200 mg/day). Resting metabolic rate, anthropometry, body composition and metabolic responses during a 30-minute steady state exercise test (55% V̇O2max) were measured at baseline and repeated post intervention. There was no effect of either supplement alone, or in combination on body mass (Baseline vs post intervention - RK: 82.5 ± 3.8 vs 81.6 ± 3.9, CGE: 81.1 ± 3.0 vs 81.0 ± 3.2, RK+CGE: 75.9 ± 3.8 vs 74.5 + 4.0, Control: 76.7 ± 4.1 vs 76.3 ± 4.2kg (p>0.05)) or body fat (Baseline vs post intervention - RK: 25.6 ± 3.3 vs 25.9 ± 2.7, CGE: 28.2 ± 4.3 vs 28.7 ± 4.2, RK+CGE: 33.0 ± 3.8 vs 32.4 ± 3.7, Control 25.8 ± 3.6 vs 25.8 ± 3.3% (p>0.05)). Similarly, no effect on substrate utilisation was observed either at rest (Baseline vs post intervention RER - RK: 0.83 ± 0.02 vs 0.84 ± 0.01, GCE: 0.84 ± 0.02 vs 0.83 ± 0.01, RK+GCE: 0.85 ± 0.03 vs 0.82 ± 0.03, Control: 0.82 ± 0.02 vs 0.84 ± 0.01 (p>0.05)) or during exercise (Baseline vs post intervention RER - RK: 0.89 ± 0.01 vs 0.87 ± 0.02, GCE: 0.90 ± 0.02 vs 0.90 ± 0.01, RK+GCE: 0.85 ± 0.01 vs 0.84 ± 0.01, Control: 0.86 ± 0.02 vs 0.87 ± 0.02 (p>0.05)). In conclusion, this study demonstrated that 8-weeks of supplementation with raspberry ketone, green coffee extract and a combination of these supplements had no effect on body mass, body composition or substrate utilisation.