This thesis deals with current issues in the field of acute ischemic stroke. The main objective has been to proof the effectiveness,and safety of intra-arterial treatment in patients with acute ischemic stroke. MR CLEAN was the first study to proof the safety,and effectiveness of intra-arterial treatment in patients presenting with an acute ischemic stroke caused by a large vessel,occlusion treatable within six hours after symptom onset. Together with the results from the other recently published trials,and the subsequent meta-analysis, intra-arterial treatment has become standard of care for acute ischemic stroke and has been,incorporated in national and international guidelines. Intra-arterial treatment will have an enormous impact on health care,systems and on the health and quality of life of countless patients across the globe.,
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Intra‐arterial treatment for acute ischemic stroke