The results of a 2001 survey of Nigerianmanufacturing firms, underscore the importance of givingbusiness managers, both a reason, and the means to takeaction on the implications of HIV/AIDS. Using regressionmethods to analyze which characteristics of the firmsaffected the probability about taking action on theepidemic, five variables, statistically predicted suchaction: known working individual, currently an HIV-positive;deceased individual, or who no longer works with the firmdue to HIV/AIDS; information received by the firm onHIV/AIDS in the last year; the industrial importance of thefirm; and, an on-site medical clinic at the firm. Thesefindings indicate that first hand experience on theepidemic, is a determining factor for behavioral change,consistent with findings in both developed, and developingcountries. Thus, it is suggested that conducting voluntary,anonymous HIV prevalence surveys in the workforce, maybecome the practice that prompts managers to take action,and, findings also supported the efforts that would promotecounseling, and testing, as an intervention to reduce riskybehavior, therefore helping prevent the spread of the disease.