This case study seeks to understand howthe Lagos Eko Secondary Education Project (Eko Project)tailored international best practices to leverage impactthrough education sector reforms in Lagos State’s publicsecondary school system. These best practices include anintensive utilization of evidence-based policy making, thegranting of autonomy to a variety of stakeholders togetherwith the expectation of accountability for results,community participation, incentives for reform, support forpublic-private partnerships (PPPs), and adaptiveimplementation. Research methods focus on the Science ofDelivery case study guidelines, drawing on semi-structuredinterviews and focus group discussions with key stakeholdersto better understand the implementation process and analyzethe causal mechanisms for results achieved. The case studyhighlights four key contributors to the Eko Project’spolitically savvy, locally tailored and adaptive deliveryapproach: (i) it managed to build on collective leadershipalong the entire delivery chain, from the politicalleadership of the governor down to the professionalleadership of classroom teachers; (ii) it bounced back froma setback in outcomes by strengthening data collection andanalysis of results; (iii) it struck the right balancebetween external and internal implementation mechanisms tomake the most of established institutions; and (iv) it aimedat macro-level impact by reaching down to individuallearning achievements.