This document describes the operation and use of the Portable Nondestructive Assay (NDA) II equipment for use in the determination of (sup235)U enrichment of uranium of various chemical forms and contained in different vessels. The Portable NDA II is the next generation NDA equipment assembled by Lawrence Livermore National Laboratory (LLNL) for the Department of Energy's Highly Enriched Uranium - Transparency Implementation Program (HEU-TIP). Presented in this document is an overview of the enrichment measurement methodology, instructions for the assembly and disassembly of the equipment, description of and user's guide for the UMeter enrichment meter software and a section on system troubleshooting. Also included herewith are facility-specific information and parameters for each of the HEU-processing sites subject to the HEU Transparency Implementation Program.