On April 7, 2004 Hanford's Waste Management organization initiated a draft site report (Occurrence Report RL-PHMC-General-2004-0001) that a Potential Inadequacy in the Safety Analysis (PISA) had been determined to exist due to issues involving the validation and/or verification of CFAST software used to develop documents supporting the safety basis. In response to the PISA, each Hanford Project Organization instituted a USQ review and performed a safety review. This report documents the results of an analysis performed to determine if sufficient verification and validation test data exist to support the use of the CFAST code for Safety Analysis at the Hanford Site. The analysis also identifies critical features, capabilities and interfaces to be validated for Hanford Site applications. The report is prepared in response to the Fluor Hanford Evaluation of the PISA (FH-0401 116).