A nonlinear kinetic-fluid model for high plasmas with multiple ion species which can be applied to multiscale phenomena is presented. The modelects due to nite ion Larmor radius (FLR), wave-particle resonances, magnetic particle trapping, etc. in the framework of simple fluid descriptions. When further restricting to low frequency phenomena with frequencies less than the ion cyclotron frequency the kinetic-fluid model takes a simpler form in which the fluid equations of multiple ion species collapse into single-fluid density and momentumects are introduced via plasma pressure tensors for ions and electrons which are computed from particle distribution functions that are governed by the Vlasov equation or simplied plasma dynamics equations such as the gyrokinetic equation.