At present, the Nizhnekanskiy granitoid massif in Krasnoyarsk Region, Russia, is under consideration as a prospective site for building the HLW underground repository in Russia. In order to develop technology of HLW underground disposal, it is important to evaluate chemical durability of different waste forms, in particular, actinide ceramics, under conditions of a real geological environment of selected site. Although different ceramic waste forms such as those based on: zircon, zirconia and titanate pyrochlore were developed and justified for actinide immobilization, there is still a lack of information concerning actinide release from their matrices in ion-saturated solutions occurred in granitoid massif. Main goal of this paper is to discuss first preliminary results of alteration experiments simulating actinide ceramic corrosion by underground water of granitoid rocks.