This paper describes the approach of dealing with an historic legacy of pharmaceutical manufacturing operations, which arose as a result of the temporary cessation of sea disposal in 1983. The result of that cessation was an accumulation of 1,000 reinforced concrete lined steel drums containing intermediate level nuclear waste of mixed chemical and physical form. Included are the steps taken which established a policy, the resulting strategy and the unique and innovative means by which the plan was implemented. The objective was to reduce the financial liability of the waste contained within the drums by removing those portions that had already decayed, segregating the waste in terms of non disposable and disposable isotopes, size reduction and long-term storage of the residues in a retrievable waste form. As part of this process the Company established a UK strategy which would ensure that the Company was self sufficient in radioactive waste handling storage facilities until the provision of a national facility, currently predicted to be approximately 2040.