This is the eleventh Quarterly Technical Report for DOE Cooperative Agreement No: DE-FC26-00NT40954. The goal of the project is to develop and demonstrate a software framework to enable virtual simulation of Vision 21 plants. During the last quarter much progress was made in software development. The CO wrapper for the integration of Alstom Power proprietary code INDVU was upgraded to CO V1.0.0 and was successfully integrated with an Aspen Plus flowsheet. The V21-Controller and the Fluent CO wrapper were upgraded to CO V.1.0.0, and the testing and debugging of the upgraded V21-Controller was completed. Two Aspen Plus analysis tools (sensitivity analysis and optimization) were successfully tested in an integrated simulation. Extensive testing of the integrated software was continued. A list of suggested enhancements was given to the software development team. Work on software documentation was started. Work on preparing the release version progressed: Several enhancements were made in the V21-Controller and the Fluent Configuration Wizard GUIs. Work to add persistence functionality to the V21-Controller was started. During the last quarter good progress was made in software demonstration. Demo Case 1 simulations were completed. This case, a conventional steam cycle with a CFD model representing the boiler module, was successfully demonstrated at 9 distinct load points from 33 MW to 19 MW. Much progress was made with Demo Case 2. Work on adding a CO wrapper to the HRSGSIM code was completed, and integrated simulations with the HRSGSIM code were conducted. The CFD heat exchanger model for Demo Case 2 was calibrated with HRSGSIM results.