Cost is one of the biggest obstacles to sending humans to Mars. However, spacecraft costs are typically not estimated until after the preliminary vehicle and mission concepts have been designed. By automating the cost estimation process, the effect of any change in vehicle or mission design on the mission cost can be determined more efficiently. This paper describes an extension to the tool SAPE (Systems Analysis for Planetary Entry, Descent, and Landing). This extension integrates the cost modeling software SEER-H (System Estimation and Evaluation of Resources-Hardware) with a number of systems analysis tools. This new method is used to analyze several trade spaces of a HIAD (Hypersonic Inflatable Aerodynamic Decelerator) entry vehicle for human Mars missions. Key findings include quantifying the impacts of ballistic coefficient, main engine specific impulse, and thrust-to-weight ratio on the overall cost of the vehicle, and how the payload per lander and number of landers affects the cost of a campaign to Mars.