This monograph is organized to highlight the successful application of light alloys on aircraft and space launch vehicles, the role of NASA in enabling these applications for each different class of flight vehicles, and a discussion of the major advancements made in discipline areas of research. In each section, key personnel and selected references are included. These references are intended to provide additional information for technical specialists and others who desire a more in-depth discussion of the contributions. Also in each section, lessons learned and future challenges are highlighted to help guide technical personnel either in the conduct or management of current and future research projects related to light-weighting advanced air and space vehicles.