Update: Antarctic Winterover as an Analog for Spaceflight Immune Dysregulation

Makedonas, George ; Mehta, Satish K ; Krieger, Stephanie S ; Chouker, Alexander ; Basner, Mathias ; Stahn, Alexnder ; Pierson, Duane L ; Crucian, Brian E

关键词: ANTARCTIC REGIONS;    LYMPHOCYTES;    CYTOLOGY;    ASTRONAUTS;    VIRUSES;    SPACE FLIGHT;    IMMUNE SYSTEMS;    IMMUNITY;    FREQUENCIES;   

RP-ID  :  JSC-E-DAA-TN64744

学科分类：医学（综合）

美国|英语

来源: NASA Technical Reports Server

【 摘 要 】

Orbital spaceflight perturbs the human immune system significantly; Natural Killer (NK) and T-lymphocyte (T) cell functions are most susceptible to spaceflight-induced impairment. This loss of function may manifest in persistent latent virus reactivation (CMV, EBV, VZV), which does occur at a higher frequency in astronauts compared to earthlings.