Global food security is one of the most pressing issues of the current century, particularly for developing nations. Agricultural simulation models can be a key component in testing new technologies, seeds and cultivars etc. However, inaccurate input information, model related errors and the mode of implementation can also add to model uncertainties. In this study, the crop model is implemented in two separate fashions: a)gridded (GriDSSAT model) and b) using random spatial ensembles (RHEAS model). This is done in the Southeastern US to evaluate and understand the modelperformance over a region data availabilities. Once the model performance is assessed, multiple satellite based earth observation parameters such as soil moisture, vegetation index etc. can be assimilated into crop models to reduce input and model related uncertainties particularly in data limited regions. In this study, the National Agricultural Statistical Services (NASS) reported yield data at county levels are used for comparison andvalidation purposes. The GriDSSAT model estimation of corn yields in comparison with the reported NASS yields showed an overall RMSD of nearly 3720 (kg/ha) whereas RMSD for the RHEAS model implementation was 3550 (kg/ha). Overall the GriDSSAT model had negative bias of nearly 2400 kg/ha (except for 2013) while RHEAS had a slight positive bias of 400 kg/ha (approx.).