One element of NASA's Earth Science Technology Office is the Advanced Information Systems Technology (AIST) Program, which funds information technology development for use in the 5-20 year timeframe. The needs are identified in conjunction with the NASA research and applied sciences communities and discussions with other, forward-looking organizations, such as ESA. AIST projects must have a US lead, but collaborations with non-US organizations are encouraged. The AIST Program focuses on two major thrusts and a small collection of concept studies and solicits both evolutionary and disruptive development projects. One thrust seeks to leverage the emergence of smallsats to create constellations of instruments to examine phenomena that could not be studied before using conventional single-satellite instruments. The second thrust develops re-usable tools to support scientific investigations through the interaction with data. The study projects formulate relevant theory, bleeding-edge concepts or to articulate need statements more clearly for highly advanced work. This talk will describe the research and development funded by the AIST Program.