Passive microwave sensing is sensitive to a wide variety of geophysical parameters in the atmosphere, oceans, cryosphere, and on land. For example, spaceborne passive microwave atmospheric sounders provide the highest-impact observations for state-of-the-art weather forecast models used by meteorological agencies around the world. The ability of passive microwave sensors (radiometers) to observe day or night through cloud cover and other obstacles (wavelength dependent, of course) partially compensates for their sometimes large footprint size compared to other sensor types. Examples will be presented of radiometers deployed on the ground, on aircraft, and on satellites. Each of these environments presents different challenges in obtaining accurate observations. And while many standard radiometer designs and techniques have been developed, every user re-discovers that even the "standard" approach requires careful attention in order to achieve full potential.