A newly developed microwave (MW) land surface temperature (LST) product is used to substitute thermal infrared (TIR) based LST in the two-source energy balance approach (TSEB) for estimating ET from space. This TSEB land surface scheme, the Atmosphere Land Exchange Inverse (ALEXI) model framework, is an approach that minimizes sensitivity to absolute biases in input records of LST through the analysis of the rate of temperature change in the morning. This experiment is therefore an important test of the ability to retrieve diurnal temperature information from a constellation of satellites with microwave radiometers that together provide 6-8 observations of Ka-band brightness temperature per location per day. This represents the first ever attempt at a global implementation of ALEXI with MW-based LST and is intended as the first step towards providing all-weather capability to the ALEXI framework. The leveraging of all sky capability of MW sensors is the main motivation of this work, as TIR-based ALEXI is limited to clear sky conditions.The analysis is based on a 9-year long record of ALEXI ET generated with MW-LST as an input, which is compared to an existing implementation of the same framework with thermal infrared based LST. In this study, the MW-LST sampling is restricted to the same clear sky days as in the IR-based implementation to be able to analyse the impact of changing the LST dataset separately from the impact of sampling all-sky conditions. The results show that long-term bulk ET estimates agree with a spatial correlation of 92 for total ET in the EuropeAfrica domain and agreement in seasonal (3-month) totals of 83-97 depending on the time of year. Most importantly, the ALEXI-MW also matches ALEXI-IR very closely in terms of 3-month inter-annual anomalies, demonstrating its ability to capture the development and extent of drought conditions. The weekly ET output from the two parallel ALEXI implementations is further compared to a common ground measured reference provided by the FLUXNET consortium. Overall, they indicate a surprisingly close match in both performance metrics (correlation and RMSE) for all but the most challenging sites in terms of spatial heterogeneity and level of aridity. Moreover, merging MW- and IR-based ALEXI may provide estimates of ET with a reduced uncertainty, even during nominally clear sky days. It is concluded that a constellation of MW satellites can effectively be used to provide LST for estimating ET through TSEB, which is an important step towards all-sky satellite-based ET estimates.