Toxicological Evaluation of Realistic Emissions of Source Aerosols (TERESA): Application to Powder Plant-Derived Pm 2.5

Rohr, Annette

Electric Power Research Institute

关键词: 02 Petroleum;    Aerosols;    Sampling;    01 Coal, Lignite, And Peat;    Animals;   

DOI  :  10.2172/893180
RP-ID  :  None
RP-ID  :  FC26-03NT41902
RP-ID  :  893180

美国|英语

来源: UNT Digital Library

【 摘 要 】

This report documents progress made on the subject project during the period of March 1, 2006 through August 31, 2006. The TERESA Study is designed to investigate the role played by specific emissions sources and components in the induction of adverse health effects by examining the relative toxicity of coal combustion and mobile source (gasoline and/or diesel engine) emissions and their oxidative products. The study involves on-site sampling, dilution, and aging of coal combustion emissions at three coal-fired power plants, as well as mobile source emissions, followed by animal exposures incorporating a number of toxicological endpoints. The DOE-EPRI Cooperative Agreement (henceforth referred to as ''the Agreement'') for which this technical progress report has been prepared covers the performance and analysis of field experiments at the first TERESA plant, located in the Upper Midwest and henceforth referred to as Plant 0, and at two additional coal-fired power plants (Plants 1 and 2) utilizing different coal types and with different plant configurations. During this reporting period, data processing and analyses were completed for exposure and toxicological data collected during the field campaign at Plant 1, located in the Southeast. Toxicological results indicate some pulmonary, oxidative stress, and cardiovascular responses to certain exposure scenarios. Fieldwork at Plant 2, located in the Midwest, began on July 19, 2006. The following scenarios were completed: July 19-22: POS (oxidized + SOA); July 25-28: PONS (oxidized + neutralized + SOA); August 8-13: P (primary); August 14-15: POS; August 16-17: POS (MI rats); August 28-31: OS (oxidized + SOA, without primary particles); September 1-4: O (oxidized, no primary particles); and September 6-9: S (SOA, no primary particles). During the next reporting period, we will report complete exposure and toxicological results for Plant 2. Planning will begin for the mobile source component of the research (funded through the Harvard-EPA Center for PM Health Effects), scheduled to take place in 2008. We will also hold our annual meeting of the TERESA Technical Advisory Committee, planned for early in 2007.