Radiation Research Symposium: Chemistry and Biology of Radical-mediated Deoxyribose Oxidation in DNA

Dedon, Peter

Massachusetts Institute of Technology

关键词: Dna;    Colorado;    Radiations Oxidative Dna Damage, Free Radical, Radiation Biology;    Deoxyribose;    59 Basic Biological Sciences;   

DOI  :  10.2172/893008
RP-ID  :  DOE-ER64139Final
RP-ID  :  FG02-05ER64139
RP-ID  :  893008

美国|英语

来源: UNT Digital Library

【 摘 要 】

The $3000 of funding provided by this grant supported a well-attended (150 people) symposium at the annual Radiation Research Society meeting in Denver, Colorado, on October 19, 2005. The symposium was entitled, ''Chemistry and Biology of Radical-mediated Deoxyribose Oxidation in DNA'', and it focused on the chemistry of damage to deoxyribose caused by radiation and other oxidants, and the role of this chemistry in the biological consequences and responses of cells to chemical and physical insults. The talks highlighted the emerging evidence for a major role for deoxyribose oxidation in the toxic effects of ionizing radiation.