LATERAL GENE TRANSFER AND THE HISTORY OF BACTERIAL GENOMES

Ochman, Howard

University of Arizona

关键词: Amplification;    Environmental Microbioogy;    Genes;    59 Basic Biological Sciences;    Strains Bacterial Diversity;   

DOI  :  10.2172/876510
RP-ID  :  DOE-ER63147-1
RP-ID  :  FG03-01ER63147
RP-ID  :  876510

美国|英语

来源: UNT Digital Library

【 摘 要 】

The aims of this research were to elucidate the role and extent of lateral transfer in the differentiation of bacterial strains and species, and to assess the impact of gene transfer on the evolution of bacterial genomes. The ultimate goal of the project is to examine the dynamics of a core set of protein-coding genes (i.e., those that are distributed universally among Bacteria) by developing conserved primers that would allow their amplification and sequencing in any bacterial taxa. In addition, we adopted a bioinformatic approach to elucidate the extent of lateral gene transfer in sequenced genome.