科技报告详细信息
Linking Molecular Events to Cellular Responses at Low Dose Exposures | |
Weber, Thomas J. ; Colburn, Nancy H. ; Bowman, Michael K. | |
Pacific Northwest National Laboratory (U.S.) | |
关键词: 63 Radiation, Thermal, And Other Environmental Pollutant Effects On Living Organisms And Biological Materials; Neoplasms; 54 Environmental Sciences; Radiations; Risk Assessment; | |
DOI : 10.2172/833477 RP-ID : EMSP-69941--2000 RP-ID : 833477 |
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美国|英语 | |
来源: UNT Digital Library | |
【 摘 要 】
The studies proposed in this project are to define thresholds in cell signaling pathways that are required for cellular transformation and may be targeted by low-dose radiation. Defining thresholds in transformation-related signal transduction pathways that are sensitive to low-dose radiation would be an important advancement in risk assessment and could be used to demonstrate nonlinear relationships between low-dose radiation and cancer.
【 预 览 】
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833477.pdf | 10KB | download |