Markers of the Low Dose Radiation Response

Dynan, William S.

United States. Department of Energy.

关键词: Repair;    Dna;    59 Basic Biological Sciences;    Biology;    61 Radiation Protection And Dosimetry;   

DOI  :  10.2172/833473
RP-ID  :  EMSP-2001--69906
RP-ID  :  FG07-99ER62875
RP-ID  :  833473

美国|英语

来源: UNT Digital Library

【 摘 要 】

One of the major challenges in the field of radiation biology is to correlate the results of biochemical studies with the process of DNA repair as it occurs in the living cell. The overall goal of this project is to develop better methods for visualizing DNA doublestrand breaks and double-strand break repair complexes in situ, in irradiated cells. Technologies are particularly needed to study repair complexes induced by low doses of radiation, where only one or a few breaks may be present.